Several search techniques are common to a variety of licensed databases - subject headings, truncation, Boolean operators, and limits. Depending on your topic, there may also be search filters available to apply to one or more databases. See these Medline Ovid tutorials for an overview.
You may find it helpful to use a table in Word or Excel to track the subject headings and keywords you've used for concepts. Also, most licensed databases include an option to save your search history, and to set up email alerts when new articles are found on your topic.
Many databases include a system of subject headings (which may also be called descriptors). These terms are added to articles by human indexers to make it easier to search for all the articles on a particular concept. MeSH (Medical Subject Headings) are used in MEDLINE. EMBASE, CINAHL, and many other databases have their own systems of subject headings; these can usually be found in the thesaurus section of a database.
For a thorough literature search, you should search with both keywords and subject headings. Some databases or grey literature search sources only allow searching by keyword. A useful technique to utilize in keyword searching is truncation (or wildcards). This is when you use a character at the end or within a word to search for different spellings. Many databases use * as the truncation symbol.
Most databases support searching for exact phrases by putting words in quotes.
Some databases allow adjacency searching, which will find words close to each other, but in any order.
Check the help section of the database you're using to find out which of these features are available and how to use them.
Boolean operators are useful for combining subject headings and keywords.
NOT is another operator which will find one concept while excluding another. Use with caution because you may exclude relevant articles this way.
Most databases include various limiters. These usually qualify human characteristics such as gender, ethnicity or age or publication characteristics such as language, publication date, study design, or type of publication.
One way to limit to human studies in Ovid MEDLINE is to combine this line with the last set of your search:
NOT (exp animals/ NOT (exp animals/ AND humans/)